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呂健宏副教授兼海生所所長

 

 

現  職

 

國立臺灣海洋大學海洋生物研究所副教授

 

 

國立臺灣海洋大學生命科學暨生物科技學系合聘副教授

 

 

國立臺灣海洋大學海洋生物科技博士學位學程副教授

 

學  歷

 

 

國立台灣大學動物學研究所博士

 

 

研究專長

 

 

甲殼類動物疫病學、分子生物學、蝦類病毒學

 

 

任教課程

 

 

生物電子顯微鏡學及實習、甲殼類動物疫病學、細胞學

 

 

  

 

 

甲殼類疫病學研究室

 

 

聯絡方式

 

 

電話 (02) 24622192分機 5316 (辦公室)5313(實驗室)

傳真 (02) 2463-3152

 

 

電子信箱

 

 

jiholeu@ntou.edu.tw

 

 

近五年研究計畫

 

pdf檔案

 

學術性著作

 

pdf檔案

 

研究室影片介紹

 

 

 

甲殼類疫病學研究室

 

 

近五年期刊論文Publications

 

2017

1.   CT Tseng, JH Leu, IJ Cheng (2017) On the genetic diversity of two species of the genus Ozobranchus (Hirudinida; Ozobranchidae) from the Atlantic and Pacific oceans. Journal of the Marine Biological Association of the United Kingdom 98(4): 955-960. (DOI: 10.1017/S0025315416001958) (SCI)

2015

 1.  JH Leu, KF Liu, KY Chen, SH Chen, YB Wang, CY Lin, CF Lo (2015)The novel white spot syndrome virus-induced gene, PmERP15, encodes an ER stress- responsive protein in black tiger shrimp, Penaeus monodon. Developmental and Comparative Immunology 49(2): 239-248. (SCI)

2.  WJ Liu, CF Lo, GH Kou, JH Leu, YJ Lai, LK Chang, YS Chang (2015) The promoter of the white spot syndrome virus immediate-early gene WSSV108 is activated by the cellular KLF transcription factor. Developmental and Comparative Immunology 49(1): 7-18. (SCI)

2014

1.    Liu W.J., Shiung H.J., Lo C.F., Leu J.H., Lai Y.J., Lee T.L., Huang W.T., Kou G.H., Chang Y.S. Characterization and interactome study of white spot syndrome virus envelope protein VP11. PLoS One. 2014 Jan 21;9(1):e85779.

2.    Huang P.Y., Leu J.H., Chen L.L. A newly identified protein complex that mediates white spot syndrome virus infection via chitin-binding protein. J Gen Virol. 2014 Aug;95(Pt 8):1799-808.

3.    Yang Y.T., Lee D.Y., Wang Y., Hu J.M., Li W.H., Leu J.H., Chang G.D., Ke H.M., Kang S.T., Lin S.S., Kou G.H., Lo C.F. The genome and occlusion bodies of marine Penaeus monodon nudivirus (PmNV, also known as MBV and PemoNPV) suggest that it should be assigned to a new nudivirus genus that is distinct from the terrestrial nudiviruses. BMC Genomics. 2014 Jul 25;15:628.

4.    Liu W.J., Lo C.F., Kou G.H., Leu J.H., Lai Y.J., Chang L.K., Chang Y.S. The promoter of the white spot syndrome virus immediate-early gene WSSV108 is activated by the cellular KLF transcription factor. Developmental and Comparative Immunology. 2014 Nov 6;49(1):7-18.

 

2013

1.    Leu J.H., Lin S.J., Huang J.Y., Chen T.C., Lo C.F. A model for apoptotic interaction between white spot syndrome virus and shrimp. Fish & Shellfish Immunology 2013 Apr;34(4):1011-7. Review paper.

2.    Huang Z.J., Kang S.T., Leu J.H., Chen L.L. Endocytic pathway is indicated for white spot syndrome virus (WSSV) entry in shrimp. Fish Shellfish Immunol. 2013 Sep;35(3):707-15.

 

2012

1.    Huang J.Y., Liu W.J., Wang H.C., Lee D.Y., Leu J.H., Wang H.C., Tsai M.H., Kang S.T., Chen I.T., Kou G.H., Chang G.D., Lo C.F. Penaeus monodon Thioredoxin Restores the DNA Binding Activity of Oxidized White Spot Syndrome Virus IE1. Antioxid Redox Signal. 2012; Sep 15;17(6):914-26.

2.    Huang H.T., Leu J.H., Huang P.Y., Chen L.L. A putative cell surface receptor for white spot syndrome virus is a member of a transporter superfamily. PLoS One. 2012;7(3):e33216.

3.    Leu J.H., Chen Y.C., Chen L.L., Chen K.Y., Huang H.T., Ho J.M., Lo C.F. Litopenaeus vannamei inhibitor of apoptosis protein 1 (LvIAP1) is essential for shrimp survival. Developmental and Comparative Immunology. 2012 Sep;38(1):78-87.

 

2011

1.    Leu J.H., Chen S.H., Wang Y.B., Chen Y.C., Su S.Y., Lin C.Y., Ho J.M., Lo C.F. A Review of the Major Penaeid Shrimp EST Studies and the Construction of a Shrimp Transcriptome Database Based on the ESTs from Four Penaeid Shrimp. Mar Biotechnol (NY). 2011 Aug;13(4):608-21. Review paper

2.    Nupan B., Phongdara A., Saengsakda M., Leu J.H., Lo C.F. Shrimp Pm-fortilin inhibits the expression of early and late genes of white spot syndrome virus (WSSV) in an insect cell model. Developmental and Comparative Immunology 2011 Apr;35(4):469-75.

3.    Huang W.J., Leu J.H., Tsau M.T., Chen J.C., Chen L.L. Differential expression of LvHSP60 in shrimp in response to environmental stress. Fish and Shellfish Immunology 2011; 30(2):576-82.

4.   Lin Y.R., Hung H.C., Leu J.H., Wang H.C., Kou G.H, Lo C.F. The role of aldehyde dehydrogenase and hsp70 in suppression of white spot syndrome virus replication at high temperature. Journal of Virology. 2011;85(7):3517-25.

 

 

近五年研討會論文(Conference posters or papers

 

1.     MH Wu, JH Leu, HY Chou (2013) A comparative study between ranavirus and megalocytivirus infections in oragns-spotted grouper (Epienphelus coioides). 9th East China Sea Conference: International Conference on the Marine Biodiversity and Environmental Fisheries Science of the East China Sea. 29 Sep - 1 Oct, Keelung, Taiwan. (poster presentation)

8.  MF Lee, JD Huang, JH Leu, SY Lee, SM Liu (2017) The structure of the accessory nidamental gland of pharaoh cuttlefish (Sepia pharaonis) and isolation of the symbiotic bacteria. Annual Congress of the Fisheries Society of Taiwan. 17 Jan, Keelung, Taiwan. (poster presentation)

9.  MF Lee, JD Huang, SY Lee, JH Leu, SM Liu (2017) The isolation of the symbiotic bacteria from the accessory nidamental glands and eggs of the pharaoh cuttlefish, Sepia pharaonis (Cephalopoda: Sepiidae). 9th Asian Symposium on Microbial Ecology (ASME). 26-28 April, Busan, Korea. (poster presentation) 

10. MF Lee, JD Huang, SY Lee, JH Leu, SM Liu (2017) Isolation of the Symbiotic Bacteria from the Accessory Nidamental Glands and the Egg cases of the Pharaoh Cuttlefish, Sepia pharaonis (Cephalopoda: Sepiidae). The Annual Meeting of Taiwan Society of Microbial Ecology (TSME). 8 Sep, Taichung, Taiwan. (poster presentation)

11呂健宏、蔡志明、周信佑 (2017) 點帶石斑魚19CC趨化素基因之鑑定與基因表現分析。第八屆海峽兩岸魚類生理與養殖研討會。1022-25,廈門,中國。

12. JH Leu, JH Tsai, HY Chou (2018) Identification and expression analysis of 19 CC chemokine genes in orange-spotted grouper Epinephelus coioides. Annual Congress of the Fisheries Society of Taiwan. 19 Jan, Kaohsiung, Taiwan. (oral presentation)

13. JH Leu, JH Tsai, HY Chou (2018) Identification and expression analysis of 19 CC chemokine genes in orange-spotted grouper Epinephelus coioides. Asian-Pacific Aquaculture 2018 (APA18). 23-26 April, Taipei, Taiwan. (oral presentation)

 

專書或專利Books or Patents

 

1.    Leu J.H., Tsai J.M., Lo C.F. White spot syndrome virus. Encyclopedia of Virology, third Edition. Elsevier 2008.

2.    Leu J.H., Yang F., Zhang X., Xu X., Kou G.H., Lo C.F. Lesser Known Big DNA Viruses: Whispovirus. Current Topics in Microbiology and Immunology 328 (edited by James L. Van Etten) p197-227. Springer-Verlag Berlin Heidelberg 2009.