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Associate Professor Leu Jiann-Horng







Associate Professor


Highest Degree



Ph.D., Natl. Taiwan Univ., R.O.C.



Field of Specialization



Crustacean diseases and immunology, Molecular biology, shrimp virology






886-2-2462-2192 ext 5316 or 5313


Fax 886-2-2463-3152

















Labs Video Presentation



Film Introduction






1.   CT Tseng, JH Leu, IJ Cheng (2017) On the genetic diversity of two species of the genus Ozobranchus (Hirudinida; Ozobranchidae) from the Atlantic and Pacific oceans. Journal of the Marine Biological Association of the United Kingdom 98(4): 955-960. (DOI: 10.1017/S0025315416001958) (SCI)


1.Leu J.H., Liu K.F., Chen K.Y., Chen S.H., Wang Y.B., Lin C.Y., Lo C.F. 2014. The novel white spot syndrome virus-induced gene, PmERP15, encodes an ER stress- responsive protein in black tiger shrimp, Penaeus monodon. Developmental and Comparative Immunology. 2015 Apr;49(2):239-48.



1.Liu W.J., Shiung H.J., Lo C.F., Leu J.H., Lai Y.J., Lee T.L., Huang W.T., Kou G.H., Chang Y.S. Characterization and interactome study of white spot syndrome virus envelope protein VP11. PLoS One. 2014 Jan 21;9(1):e85779.

2.Huang P.Y., Leu J.H., Chen L.L. A newly identified protein complex that mediates white spot syndrome virus infection via chitin-binding protein. J Gen Virol. 2014 Aug;95(Pt 8):1799-808.

3.Yang Y.T., Lee D.Y., Wang Y., Hu J.M., Li W.H., Leu J.H., Chang G.D., Ke H.M., Kang S.T., Lin S.S., Kou G.H., Lo C.F. The genome and occlusion bodies of marine Penaeus monodon nudivirus (PmNV, also known as MBV and PemoNPV) suggest that it should be assigned to a new nudivirus genus that is distinct from the terrestrial nudiviruses. BMC Genomics. 2014 Jul 25;15:628.

4.Liu W.J., Lo C.F., Kou G.H., Leu J.H., Lai Y.J., Chang L.K., Chang Y.S. The promoter of the white spot syndrome virus immediate-early gene WSSV108 is activated by the cellular KLF transcription factor. Developmental and Comparative Immunology. 2014 Nov 6;49(1):7-18.



1.Leu J.H., Lin S.J., Huang J.Y., Chen T.C., Lo C.F. A model for apoptotic interaction between white spot syndrome virus and shrimp. Fish & Shellfish Immunology 2013 Apr;34(4):1011-7. Review paper.

2.Huang Z.J., Kang S.T., Leu J.H., Chen L.L. Endocytic pathway is indicated for white spot syndrome virus (WSSV) entry in shrimp. Fish Shellfish Immunol. 2013 Sep;35(3):707-15.



1.Huang J.Y., Liu W.J., Wang H.C., Lee D.Y., Leu J.H., Wang H.C., Tsai M.H., Kang S.T., Chen I.T., Kou G.H., Chang G.D., Lo C.F. Penaeus monodon Thioredoxin Restores the DNA Binding Activity of Oxidized White Spot Syndrome Virus IE1. Antioxid Redox Signal. 2012; Sep 15;17(6):914-26.

2.Huang H.T., Leu J.H., Huang P.Y., Chen L.L. A putative cell surface receptor for white spot syndrome virus is a member of a transporter superfamily. PLoS One. 2012;7(3):e33216.

3.Leu J.H., Chen Y.C., Chen L.L., Chen K.Y., Huang H.T., Ho J.M., Lo C.F. Litopenaeus vannamei inhibitor of apoptosis protein 1 (LvIAP1) is essential for shrimp survival. Developmental and Comparative Immunology. 2012 Sep;38(1):78-87.



1.Leu J.H., Chen S.H., Wang Y.B., Chen Y.C., Su S.Y., Lin C.Y., Ho J.M., Lo C.F. A Review of the Major Penaeid Shrimp EST Studies and the Construction of a Shrimp Transcriptome Database Based on the ESTs from Four Penaeid Shrimp. Mar Biotechnol (NY). 2011 Aug;13(4):608-21. Review paper

2.Nupan B., Phongdara A., Saengsakda M., Leu J.H., Lo C.F. Shrimp Pm-fortilin inhibits the expression of early and late genes of white spot syndrome virus (WSSV) in an insect cell model. Developmental and Comparative Immunology 2011 Apr;35(4):469-75.

3.Huang W.J., Leu J.H., Tsau M.T., Chen J.C., Chen L.L. Differential expression of LvHSP60 in shrimp in response to environmental stress. Fish and Shellfish Immunology 2011; 30(2):576-82.

4.Lin Y.R., Hung H.C., Leu J.H., Wang H.C., Kou G.H, Lo C.F. The role of aldehyde dehydrogenase and hsp70 in suppression of white spot syndrome virus replication at high temperature. Journal of Virology. 2011;85(7):3517-25.



Conference posters or papers


1.Leu J.H., Chen K.Y., Huang H.T. “Cloning, expression analysis, and silencing study of three inhibitor of apoptosis protein genes (IAP) from Litopenaeus vannamei shrimp” in 8th Symposium on Diseases in Asian Aquculture (DAA VIII, 21 - 25 November 2011). Mangalore, India. Oral presentation.

2.Leu J.H. , Chen K.Y., Lai J.H. “Identification of hematopoiesis-related genes in Litopenaeus vannamei” in 12th Congress of International Society of Developmental and Comparative Immunology (ISDCI, 9-13 July 2012). Fukuoka city, Japan. Oral presentation.

3.Wu M. H., Leu J. H., Chou H. Y. “A comparative study between ranavirus and megalocytivirus infections in oragns-spotted grouper (Epienphelus coioides)” in 9th East China Sea Conference: International Conference on the Marine Biodiversity andEnvironmental Fisheries Science of the East China Sea (29 Sep - 1 Oct). Keelung, Taiwan. Poster presentation.



Books or Patents


1.Leu J.H., Tsai J.M., Lo C.F. White spot syndrome virus. Encyclopedia of Virology, third Edition. Elsevier 2008.

2.Leu J.H., Yang F., Zhang X., Xu X., Kou G.H., Lo C.F. Lesser Known Big DNA Viruses: Whispovirus. Current Topics in Microbiology and Immunology 328 (edited by James L. Van Etten) p197-227. Springer-Verlag Berlin Heidelberg 2009.